- Shin-Chitose to Wakkanai 55 minutes ANA 2 times a day
- Haneda to Wakkanai 115 minutes ANA 1 time a day (2 times in summmer)
- Haneda to Asahikawa 95 minutes ANA, JAL and AIRDO 7 times a day
- Okadama to Rishiri 55 minutes HAC 1 times a day
- Shin-Chitose to Rishiri 50 minutes HAC 1 times a day(Seasonal operation)
- Sapporo to Wakkanai 5hr to 5hr 20 minutes, 3 times a day
- Asahikawa to Wakkanai 3hr 40minutes, 3 times a day
- Sapporo to Wakkanai 5hr to 5hr 50 minutes, 6 times a day (Soya Bus)
- Sapporo to Esashi 5hr, 1 time a day (Soya Bus)
- Sapporo to Horonobe 4hr 50minutes and Toyotoi 5hour 10minutes, 4 times a day (Engan Bus)
- Wakkanai to Sarufutsu 1hr 50minutes and Hamatonbetsu 2hr 30minutes, 6 times a day (Soya Bus)
- From Sapporo to Rumoi by Do-O and Fukagawa-Rumoi Highway via Fukagawa Junction. From Rumoi to Tesiho by Route 232 and from Teshio to Wakkainai by Do-do 106.
- From Asahikawa to Wakkanai, get off Do-O highway at Shibetsu-Kenbuchi Interchange and go to Route 40.
- Wakkanai ⇔ Oshidomari (about 1 hour 40 minutes) Heartland Ferry
- Wakkanai ⇔ Kafuka (about 1 hour 55 minutes) Heartland Ferry
- Oshidomari ⇔ Kafuka (about 40 minutes) Heartland Ferry